Meet the science behind what we do. Here are some of the research articles behind what we do.

Exercise as a treatment for chronic low back pain

Rainville J, Hartigan C, Martinez E, Limke J, Jouve C, Finno M.
Exercise as a treatment for chronic low back pain. Spine J 2005; 4: 106-115.


Clinical Implications for N-GPS: Exercise is SAFE for individuals with back pain and it will not increase the risk of future back injuries or work absence. There is significant evidence to suggest exercise will lower pain scores while additionally decreasing the behavioral, cognitive, and disability components of low back pain syndromes.
Exercise alone can have all these benefits to chronic low back pain. When combined with the N-GPS biopsychosocial treatment approach these effects can be compounded.
Kernan T, Rainville J. Observed outcomes associated with a quota-based exercise approach on measures of kinesiophobia in patients with chronic low back pain. J Orthop Sports Phys Ther 2007; 37(11):679-687
Kinesiophobia decreases during an intensive physical therapy program when exercises are performed in a quota-based manner. Additionally, fear of injury decreases which can have a positive impact on disability.
The time-based, ability-based approach to N-GPS exercise meets the definition of quota-based exercise and demonstrates similar results showing an average improvement of 110% in functional exercise and 10% reduction in Oswestry Disability Index

Can group-based reassuring information alter low back pain behavior?

Frederiksen P, et al. Can group-based reassuring information alter low back pain behavior?
A cluster-randomized controlled trial. PLoS ONE 12(3): e0172003. pone.0172003

Providing people who suffer from chronic low back pain with simple, reassuring, information about low back pain significantly decreases disability behavior. This effect is enhanced in a group environment.
It is recommended that all N-GPS treatments take place in a group setting. All treatments provide basic education about pain research to decrease kinesiophobia and dysfunctional cognition associated with the chronic pain cycle which has a positive impact on patient perception of disability.
Sletten CD, et al. Economic Analysis of a comprehensive pain rehabilitation program: a collaboration between Florida Blue and Mayo Clinic Florida. Pain Med 2015; 16:898-904
Use of a comprehensive outpatient pain rehabilitation program results in decreased medical costs up to at least 18 months after discharge. N-GPS provides many aspects of an outpatient pain rehabilitation program at an exceedingly low cost. One of the primary goals of N-GPS is to increase volume and decrease cost without compromising positive outcomes. A significant reduction in consumption of medical resources and associated costs is beneficial to both the patient and insurance companies alike.

Running-induced systemic cathepsin B secretion is associated with memory function.

Moon HY, et al. Running-induced systemic cathepsin B secretion is associated with memory function. Cell Metab. 2016 Jun 21. Pii:S1550-4131(16)30247-9.
Berg U, Bang P. Exercise and circulating insulin-like growth factor-1. Horm Res 2004: 62 (suppl1): 50-58.

When exercise is performed at a high enough intensity the exercised muscles release the neural active proteins insulin-like growth factor 1 (IGF-1) and cathespsin B. These proteins are capable of penetrating the blood-brain barrier to enhance neurogenesis and brain function. “Moderate to Intense” movement makes you faster, stronger, smarter AND accelerates neuroplasticity.
N-GPS is a high-intensity Continuous Movement Therapy which allows these neural active proteins to be released and takes full advantage of the enhanced neurogenesis by combining all exercise with biopsychosocial pain education. Education while in this neutrally active state enhances the desired effect of creating new, normalized neural pathways in the pain experience.

Low Back Pain Clinical Practice Guidelines

Low Back Pain Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability, and Health from the Orthopaedic Section of the American Physical Therapy Association J Orthop Sports Phys Ther. 2012;42(4):A1-A57. doi:10.2519/jospt.2012.0301

The APTA Clinical Practice Guidelines are meant to provide an evidential basis to all physical therapy treatments. A key statement in the low back pain guidelines is, “however, if your pain becomes chronic, moderate- to high-intensity exercises and progressive exercises that focus on fitness and endurance are helpful in pain management.” While this concept sounds simple, many therapists do not know how to concretely provide this kind of treatment to achieve the desired results.
N-GPS provides physical therapists with a treatment approach that is simple to implement within the four walls of their own clinics. It is a systematized approach that can be followed by any physical therapist interested in receiving the training allowing all therapists a means to provide evidence-based health care with confidence.